Yale University Graduate Studies in Chemical Biology

About Chemical Biology at Yale

Faculty

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Symposium

 

Chemistry

MCGD

MBB

Pharmacology

 

Faculty

Yale Graduate Studies in Chemical Biology combine the strengths of selected faculty from the departments of Chemistry; Molecular, Cellular & Developmental Biology; Molecular Biophysics & Biochemistry; and Pharmacology.

Faculty listing by name

Students participating in CBI Graduate Training Program at Yale University are trained by faculty whose research programs emphasize chemical approaches to study biologically important problems. Students receive interdisciplinary research experience that includes the study of natural product and combinatorial synthesis, protein folding and design, nucleic acid recognition and catalysis, and cellular biology. This training extends across the traditional boundary between chemistry and biology. Students are trained in methods that include molecular cloning, kinetic and thermodynamic measurements, NMR and mass spectrometry, synthetic organic chemistry, protein purification, and molecular modeling.

Interaction and collaboration between the students and faculty in the Chemical Biology Training Program are facilitated by a core instrumentation facility housed within Yale Chemical Genomics Center, Yale Chemical Instrumentation Core and the Yale Center for Structural Biology. Students are trained to think in chemical detail about biological phenomena, to design and synthesize molecules, and to describe macromolecular function in the language of chemistry. Faculty members in Chemical Biology Graduate Studies emphasize four major research themes covering the spectrum from bioorganic chemistry to molecular cell biology:

  1. Chemistry and Chemical Biology: Chemical Diversity, Natural Product Mode of Action, and Organic Synthesis
  2. Nucleic acid catalysis and recognition
  3. Protein design, recognition, function and characterization
  4. Cell Biology and protein biochemistry of intracellular processes

Faculty listing by name

1. Chemistry
Craig Crews
Glenn Micalizio
Scott Miller
Alanna Schepartz
David Spiegel
Ann Valentine

 

2. Nucleic Acids
Ronald Breaker
Dieter Söll
Scott Strobel

 

3. Proteins
Karen Anderson
Demetrios Braddock
Craig Crews
Enrique De La Cruz
William Jorgensen
Elias Lolis
Patrick Loria
Andrew Miranker
Yorgo Mordis
Lynne Regan
Alanna Schepartz
Michael Snyder

 

4. Cell Biology
Paul Forscher
Mark Hochstrasser
Art Horwich
Mark Mooseker
Tom Pollard
Joseph Schlessinger
William Sessa


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